Enter medicine name or company Start typing to retrieve search suggestions. Bowel colic and excessive respiratory secretions Bowel colic and excessive respiratory secretions may be reduced by a subcutaneous injection of hyoscine hydrobromide , hyoscine butylbromide , or glycopyrronium bromide. Find out more here. Formulations of fentanyl that are administered nasally, buccally or sublingually are also licensed for breakthrough pain. You can have diamorphine as an injection into the fatty tissue just under the skin.

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This information is intended for use by health professionals. The concomitant use of opioids with sedative medicines such as benzodiazepines or related drugs increases the risk of sedation, respiratory depression, coma and death because of additive CNS depressant effect.

Although some families may at first be diamorohine of caring for the patient at home, support can be provided by community nursing services, social services, voluntary agencies and hospices together with the general practitioner. Other side effects include dizziness, miosis, confusion, urinary retention, biliary spasm, orthostatic hypotension, facial flushing, vertigo, palpitations, mood changes, dry mouth, dependence, urticaria, pruritus and raised intracranial pressure.

Patients with hepatic or renal dysfunction: You can have diamorphine in a number of different ways. The usual initial dosage for children is 10 micrograms per kg body weight. Diamorphine is a potent opiate analgesic which has a more rapid onset of activity syrinbe morphine as the first metabolite, monoacetylmorphine, more readily crosses the blood brain barrier. Diamorphine may be used in the treatment suringe severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnoea in acute pulmonary oedema.

Constipation is a syginge cause of distress and is almost invariable after administration of an opioid analgesic.


Formulations of fentanyl that are administered nasally, buccally or sublingually are also licensed for breakthrough pain.

A corticosteroid, such as dexamethasonemay also be helpful if there is bronchospasm or partial obstruction. Initiation of an opioid analgesic should not be doee by concern over a theoretical likelihood of psychological dependence addiction.

When adjusting the dose of morphinethe number of rescue doses required and the response to them should be taken into account; increments of morphine should not exceed one-third to one-half ciamorphine the total daily dose every 24 hours.


Therapeutic doses unlikely to affect infant; withdrawal symptoms in infants of dependent mothers; breast-feeding not best method of treating dependence in offspring. When oral medication is no longer odse, diazepam given rectally, or phenobarbital by injection is continued as prophylaxis.

For the treatment of nausea and vomiting associated with cancer chemotherapy see Cytotoxic drugs. Chronic painmg regularly every four hours by subcutaneous diamorphkne intramuscular injection. Formulations of transdermal patches are available as hourly, hourly and 7-day patches, for further information see buprenorphine.

Transdermal route Transdermal preparations of fentanyl and buprenorphine are available, they are suringe suitable for acute pain or in patients whose analgesic requirements are changing rapidly because the long time to steady state prevents rapid titration of the dose. Cyclizine is particularly likely to precipitate if mixed with diamorphine or other drugs see under Mixing and Compatibility, below Metoclopramide hydrochloride can cause skin reactions.

Diamorphine | Cancer in general | Cancer Research UK

The doss is discontinued when the first oral dose riamorphine morphine is given. Risk from concomitant use syrringe sedative medicines such as benzodiazepines or related drugs Concomitant use of diamorphine and sedative medicines such as benzodiazepines or related drugs may result in sedation, respiratory depression, coma and death. In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.


Dry mouth may be caused by certain medications including opioids, antimuscarinic drugs e. You can have diamorphine as an injection into the fatty tissue just under the skin. In the case of obstructive jaundice, further measures include administration of colestyramine. Intractable cough may be relieved by moist inhalations or by regular administration of oral morphine. Other drugs classified as opioids.

Although drugs can usually be administered by mouth to control the symptoms of advanced cancer, the parenteral route may sometimes be necessary. The following are problems that may be encountered with syringe drivers and the action that should be taken:.

Pruritus, even when associated with obstructive jaundice, often responds to simple measures such as application of emollients. The equivalent subcutaneous dose of diamorphine hydrochloride is about one-third of the oral dose of morphine.

This metabolite can accumulate and result in greater pharmacological effect, because it is more active than morphine. For preparations suitable for hourly or hourly administration see modified-release preparations under morphine.

For the use of midazolam by subcutaneous infusion using a continuous infusion device see below. Drug treatment The number of drugs should be as few as possible, for even the taking of medicine may be an effort.